INDICATIONS

Altox Plus (Ivermectin & Fipronil topical solution) applied at the recommended dose level of 500 mcg/kg is indicated for the effective treatment and control of these parasites：Gastrointestinal Roundworms,

Lung Worms, Cattle Grubs, Mites, Lice, Horn Flies etc.

 

PERSISTENT ACTIVITY

Altox Plus (Ivermectin & Fipronil topical solution) has been proved to effectively control infections and to protect cattle from re-infection with: 

Oesophagostomum radiatum and Dictyocaulus viviparus for 28 days after treatment; Cooperia punctata and Trichostrongylus axei for 21 days after treatment; Ostertagia ostertagi, Haemonchus placei, Cooperia oncophora 

and Cooperia surnabada for 14 days after treatment; Damalinia bovis for 56 days after treatment.

 

TREATMENT OF CATTLE FOR HORN FLIES

Altox Plus (Ivermectin & Fipronil topical solution) controls horn flies (Haematobia irritans) for up to 28 days after dosing. For best results Altox Plus (Ivermectin & Fipronil topical solution) should be part of a parasite control program for both internal and external parasites based on the epidemiology of these parasites. Consult your veterinarian or an

entomologist for the most effective timing of applications.

 

DOSAGE

The dose rate is 1 mL for each 22 lb of body weight. The formulation

should be applied along the topline in a narrow strip extending from the withers to the tailhead.

 

ADMINISTRATION

Metering Cup with Measure-Squeeze-Pour System (250 mL (8.5 fl oz)

Container with 25 mL Metering Cup and 1 Liter (33.8 fl oz) Container

with 60 mL Metering Cup)

This pack contains 1 Metering Cup and 1 dip tube

1.Insert the dip tube into base of the Metering Cup. Leave the "slotted end" of the dip tube exposed in the bottom of the container.

2.Unscrew shipping cap from container top.

3.Screw the Metering Cup onto container top.

4.Measure: To select the correct dose rate, rotate the adjuster cap (top) in either direction to position the dose indicator to the weight of the animal you want to treat. When body weight is between markings, use the higher setting.

5.Squeeze the container gently to fill the Metering Cup to the required dose. Release your grip and any excess will return to the container.

6.Pour: Apply the full dose by tipping and pouring along the backline of the animal until the Metering Cup is empty.

7.Storage: The Metering Cup should not remain attached to the container when not in use. Detach the Metering Cup after each use and replace the shipping cap to close the container top

 

 PRECAUTIONS

•  Store at or below 25°C (77°F) and protect from light. Excursions permitted to

104°F (40°C).

• Use only in well-ventilated areas or outdoors.

• Close container tightly when not in use.

•Cattle should not be treated when hair or hide is wet since reduced efficacy may be experienced.

• Do not use when rain is expected to wet cattle within six hours after treatment.

• This product is for application to skin surface only. Do not give orally or parenterally.

• Cloudiness in the formulation may occur when IVOMEC® Pour-On is stored at temperatures below 32°F. Allowing to warm at room temperature will restore the normal appearance without affecting efficacy.

• Antiparasitic activity of ivermectin will be impaired if the formulation is applied to areas of the skin with mange scabs or lesions, or with dermatoses or adherent materials, e.g., caked mud or manure.

• Ivermectin has been associated with adverse reactions in sensitive dogs; therefore,

Altox Plus is not recommended for use in species other than cattle.

 

When to Treat Cattle with Grubs

Altox Plus (Ivermectin & Fipronil topical solution) effectively controls all stages of cattle grubs. However, proper timing of treatment is important. For the most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season. While this is not peculiar to ivermectin, destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions. Killing Hypoderma lineatum when it is in the esophageal tissues may cause bloat; killing H. bovis when it is in the vertebral canal may cause staggering or paralysis. Cattle should be treated either before or after these stages of grub development.

Cattle treated with Altox Plus (Ivermectin & Fipronil topical solution) at the end of the fly season may be re-treated with Altox Plus during the

winter without danger of grub-related reactions. For further information

and advice on a planned parasite control program, consult your veterinarian.

 

This product should not be applied to self or others because it may be irritating to human skin and eyes and absorbed through the skin. To minimize accidental skin contact, the user should wear a long-sleeved shirt and rubber gloves. If accidental skin contact occurs, wash immediately with soap and water. If accidental eye exposure occurs, flush eyes immediately with water and seek medical attention.

 

RESIDUE WARNING:

Cattle must not be treated within 48 days of slaughter for human consumption. Because a withdrawal time in milk has not been established, do not use in female dairy cattle of breeding age. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.

Environmental Safety

Studies indicate that when ivermectin comes in contact with soil it readily and tightly binds to the soil and becomes inactive over time. Free ivermectin may adversely affect fish and certain aquatic organisms. Do not permit cattle to enter lakes, streams or ponds for at least six hours after treatment. Do not contaminate water by direct application or by improper disposal of drug containers. Dispose of containers in an approved landfill or by incineration.

As with other avermectins, ivermectin is excreted in the dung of treated animals and can inhibit the reproduction and growth of pest and beneficial insects that use dung as a source of food and for reproduction. The magnitude and duration of such effects are species and life-cycle specific. When used according to label directions, the product is not expected to have an adverse impact on populations of dung-dependent insects.